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IMPORTANCE OF PERMEABILITY 'INTESTINAL

Dr. Francesco Perugini Billi

I ur gut is the real "boundary" between us and the external environment, at least on the material plane. Its primary function is not simply digest, but to transform the nature of alien what we eat in our unique physics. If this process fails, the gut is "open" and dangerous to allow flow into the body substances which undermine our sense of unity, which is the very foundation of our health. villi There are no certainties about the origins of life on our planet, but only hypothesis. Some say that was formed from nonliving matter (abiogenetic theory), others are convinced that it comes from space, carried by meteorites (cosmozoica hypothesis). However it happened, at one point, about 4 billion years ago, in Earth's primordial soup appeared aggregates of biological molecules that have begun to express a primitive feature living, growth and reproduction. A key aspect of life is the creation of a boundary that separates an "inside" and an "outside", the birth, in short, of an individuality. At first, of course, this individuality was weak, just mentioned, as in the first prokaryotes, but then with the progress of evolution has become more defined, until you reach the extraordinary complexity that is man, that expresses both an 'individual physical and mental. life so it is only possible if the very life of every moment trying not to merge with the external environment and do everything to maintain your individuality. Of course, life is not as closed systems, because it has to eat at the same time removing waste products. Between life forms and external environment, in fact, there must be a continuous exchange and physical energy. Life welcomes what is consistent and keeps what generates chaos. Even we humans live consciously or unconsciously striving to remain individuals, that is indivisible. Constantly come into contact with stimuli and elements that could damage our tissues and make us ill, such as solar radiation, wind, rain, cold, heat, microbes, pollution, etc.. Apparently, one would think that the scene of this battle between us and external aggression is our skin that covers us like a protective shell and defines our borders, but it is not. In fact, the more contact with the external environment is the case in our intestines, through the diet. This happens a lot times during the day and every time the body should pledge to transform what we are not (meat, vegetables, dairy, etc.) in what we (blood, tissues, organs, thoughts ...). In some ways, every time we eat we are also committed to defend ourselves from the "forces" inherent in foreign foods consumed. We could not slide a steak or a risotto directly into a vein, we would die for sure. Our gut has this wonderful task of "svelenare" the food we eat and turn it into blood can flow easily through our veins. Therefore, digestion occurs in the gut that has had a destructive effect on food. Its function is to kill the alien nature (animal and vegetable) food and turn it into human flesh individualized. If this does not happen, those same forces could take over our individuality and destabilize our system, once entered the body. This process involves the whole ecology of the food bowel, which is a complex system composed mainly of immune structures, flora and mucosal surfaces, in continuous interaction between them. The contact point where the interior touches the external environment, however, is found mainly in the small intestine, the only true organ of the whole digestive tract gastrointestinal tract. At this level everything is arranged the meeting with the food and its assimilation. Here, our organization has focused over 80% of the entire immune system, demonstrating that the small intestine is like a border along which deploy troops to prevent invasion. Here the flora produces enzymes that break down food. Here the everted mucosa (villi) bending increase the surface area of \u200b\u200bcontact with the nutrients and for the same reason, cells have small villi. In short, the intestinal flora reduces to a minimum food, the immune system gives a new identity and the barrier of the mucosal cells assimilate it. But the ecological system can be affected and intestinal "clearance" of food to be less efficient. The fence consists of the mucosal cells starts to drop and becomes a sort of sieve. Between a cell and the other is as if the cracks were formed. The food is beyond the normal process of digestion and assimilation and recognition through the mucosa without being tried and flows within the body, maintaining its foreign nature. This will put at risk the 'individuality of the body, the sense of unity. The consequences can range from a simple state of discomfort, heaviness, some form to severe inflammatory diseases degenerative. Even what many call "intolerance" are mostly the result of increased intestinal permeability. The "intolerance" are reactions to something, conceptual error that led to the development of a whole series of unnecessary tests , but rather a state, a condition in which the body literally "open" to the external environment unconditionally, or rather not on trial. In a leaky gut does not pass only unprocessed foods, but also toxins and microbial material (living cells and cell fragments). Often the increase in permeability is also associated with a abnormal proliferation of Candida albicans. The causes that can lead to leaky gut syndrome (SPI) are numerous, but among the most often there are serious injuries, surgeries, challenging the abuse of drugs, pollutants we eat, stress, negative emotions, the physical hardships and improper eating habits. The SPI is the basis of many unsuspected diseases such as rheumatoid arthritis, lupus erythematosus, thyroiditis, Crohn's disease, psoriasis, chronic fatigue syndrome, allergies, many skin diseases, asthma, fibromyalgia and even psychoses, neuroses infantile autism. Numerous studies have shown a link between gut and brain function. The same is the father of modern psychiatry, Frenchman Phillipe Pinel (1745-1828), said "The principal place of mental illness is the gut." As you can see, often the SPI generates power or extra-intestinal diseases, which seem to have little to do with the gut, could be as thyroiditis, an 'arthritis, repeated tonsillitis or catarrosità in the respiratory tract of a small child . Ignoring this fundamental aspect, often using their own drugs that have a gut permeabilization and that the long merely maintain the disease itself rather to heal or cause other problems occur in different organs. For example, an anti-inflammatory drug strongly permeabilizing the intestine, which is used to treat a form of rheumatism in the winter can encourage the development of allergy later in the spring. And that goes for antibiotics are used too easily, especially in children. There is currently no practical methods to diagnose the SPI that may be prescribed by our doctor or specialist. It can be suspected or inferred from a SPI medical examination and by history. Faced with a chronic or recurrent SPI is a high probability. Therapy Power - SPI is often a problem of "recognition" of the food. Our gut is very, very old and anything but adapted to the modern diet, based mostly on food devitalized, refined, processed food industry and often invented out of whole cloth. As far as my clinical experience, a low-carb diet, based on foods 'primitive', traditional and fresh, it is the best. This is to bring back our power and give the gut the food with which it has evolved and who took part in Food for a longer time: good proteins, fats, vegetables, fruit and a fair share of cereals. We must "put aside" our digestive system and give you the best foods that can recognize. Probiotics - the intestinal flora plays an important role in SPI. You must choose viable lactic acid bacteria, symbionts (human), and possibly composed of multiple strains. Some act more in the lumen (cavity) and other intestinal side more immune. Good care should last for several months and not weeks. But remember that the intestinal ecosystem is composed not only of flora, but also by the structures and mucosal immunity. Often, the only non-intervention with probiotics has the effect hoped because it has not done the same for the other components. In other words, "throw in" probiotics is not always enough in a SPI. Prebiotics - are edible vegetable fibers that once the intestines are used as food by the lactobacilli and bifidobacteria. In particular, inulin is found in vegetables and fruits and as a "fiber" is certainly present in the human diet for much longer than the fibers derived from cereals, which have appeared in recent times. Homotoxicology - this type of Homeopathy offers a very valid modern drugs for the SPI. If necessary, can be used intramuscularly and locally in mesotherapy. E 'can act on the mucosal barrier and immune component, as well as stimulate lymphatic drainage and liver. In this regard, I note that the first organ to go into overload in the case of SPI is just the liver. Phytotherapy - using herbs and herbal preparations that have a specific action on the gastrointestinal tract and whose properties are essentially soothing, anti-inflammatory, digestive, purifying, etc.. Very useful are herbal and detoxifying the liver blood. Some plants are very important in the treatment of SPI are Aloe, U tormenting NCAR, with inflammatory-immunomodulatory action. Very good are also the plants and ayurvedic preparations, such as Triphala, the Ashvagandha, the Shatavari, the ' Emblica officinalis, etc.. Supplements - one of the most important supplements required in SPI is the L-Glutamine. Enterocytes that form the mucosal barrier are very fond of glutamine, is their "fuel" preferred. L 'preferably absorbed from the intestinal lumen, rather than from the bloodstream. For this, a good supply of protein food (well represented on a diet "primitive") is very important to the health of these cells. If well fed, the enterocytes are joined together and form a viable intestinal barrier. Glutamine is also used for the production of mucus that protects the intestinal walls, and immunoglobulin A (IGAS) secretory, which are of fundamental importance for the protection of all mucosal surfaces. Glutamine in your body is well represented, but in certain situations of stress increases the demand of enterocytes and local shortages may occur. For this reason, it can sometimes be necessary to take the form of tablets. Other helpful supplements are zinc, B complex and vitamin A. In particular, zinc is a result of the minerals lacking in people suffering from dysbiosis and SPI. This element is essential for the repair, growth and integrity of the cells. As the intestinal cells are renewed quickly and have an average life of four days, a continuous and adequate supply of zinc in the intestine is very important in SPI . Digestive Enzymes - SPI in the enzymatic capacity of the intestine may be less efficient. In addition to a diet rich in fresh foods you can intervene with a integration of digestive enzymes. castor oil packs - can bring tremendous benefits. Apply heat to the abdomen 1 hour and a half cycles of 3 days a week (unless otherwise indicated by the doctor), for several months. It uses only cold-pressed oil.